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Academic & Scientific Experts Confirm Safety & Efficacy of Low Calorie Sweeteners (LCS)

  • LCS can help reduce calorie intake and assist weight/ diabetes management when used in place of sugar1
  • LCS have no adverse effect on blood glucose and insulin regulation (HbA1c, fasting and post-prandial glucose and insulin levels) in people with and without diabetes1

FAQs About Splenda®

Aren’t All Sweeteners The Same?

No! Splenda Brand Sweeteners have been voted best-tasting by consumers and are the #1 Recommended Sweetener Brand by healthcare professionals.*

Splenda Stevia is made from the best tasting part of non-GMO stevia plant leaves and erythritol — two plant based ingredients.

Splenda Original is made with sucralose from a process that starts with sugar. It does NOT contain aspartame or saccharin.

How do I know if Splenda Sweeteners are safe?

The US Food and Drug Administration regulates low-calorie sweeteners through established two main, rigorous processes to meet the FDA standard of safety – The Food Additive Review Process and the Generally Recognized as Safe process, which is used for natural products.1

Splenda products are absolutely safe and have been used by millions of people around the world since 1991. There are hundreds of studies supporting this safety message and the use of low-calorie sweeteners for weight management, diabetes management, and to reduce added sugars. Splenda Sweeteners are the #1 recommended brand of sweetener by healthcare professionals clincally treating patients.

I Heard That Using Splenda Causes Weight Gain, Diabetes, and Cravings for Sweet Foods – Is That True?

That is not true. Actually, recent studies have shown that enjoying sweet-tasting products could in fact decrease the want for additional sweets while also adding variety and flavor to foods and beverages, helping people manage weight, reduce intake of calories from added sugars, and manage blood sugar levels.2 Randomized Clinical Trials also show that low-calorie sweeteners can help people lose weight and can be useful for people managing diabetes.3, 4, 5

Will Using Splenda Impact My Gut Function?

No. A recent comprehensive review, conducted by experts in both gut microbiome and food ingredient safety research, found no evidence of any negative effects on gut health from the use of low and zero calorie sweeteners. The investigation found “clear evidence that changes in the diet unrelated to low or zero calorie sweetener consumption are likely the major determinants of change in gut microbiota numbers and phyla.”6

Taste Influences Food Choices, Eating Behaviors, and Food Intake

Consumers prefer Splenda Brand Sweeteners

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Scientific Publications Summary

Splenda Scientific Summmary

The safety and efficacy of low and zero calorie sweeteners (LNCS) have been researched for decades. This summary provides a selection of recent and well-designed scientific studies, articles and position statements in addition to a quick summary of the evaluation and regulatory review of LNCS in the U.S. and globally.

1 Ashwell, M., et. al. (2020). Nutr Res Rev. 2020 Jan 13:1-10. doi: 10.1017/S0954422419000283 *Among healthcare professionals clinically treating patients.

FAQs: 1. Roberts, A. (2016). The safety and regulatory process for low-calorie sweeteners in the United States. Physiology & Behavior. 164, Part B, 439-444. 2. (2019) Low Calorie Sweeteners and Sweet Taste. Calorie Control Council. Retrieved from: 3. When used in place of sugar; Rogers PJ, Hogenkamp PS, de Graaf C, et al. (2016) Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies. Int J of Obes 40(3), 381-394. 4. Johnston C, Stevens B, Foreyt J et al. (2013) The Role of Low-calorie Sweeteners in Diabetes. Eur Endocrinology 9(2); 96-98. 5. Rogers PJ. The role of low-calorie sweeteners in the prevention and management of overweight and obesity: evidence v. conjecture. Proc Nutr Soc, 2017 Nov;23:1-9. 6. Lobach, A. R., Roberts, A., & Rowland, I. R. (2018). Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota. Food and Chemical Toxicology, 124, 385-399.