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Splenda Brand Refutes New Safety Allegation

March 9, 2016

Recent CSPI rating on Sucralose is Misleading to Consumers

In response to the safety rating of sucralose by the Center for Science in the Public Interest (CSPI), Heartland Food Products Group, the makers of Splenda Sweeteners, wants to set the record straight. The rating is based solely on one study of mice that was conducted by the Ramazzini Institute in Italy, published in the International Journal of Occupational and Environmental Health, and does not reflect the collective body of scientific evidence proving the safety of sucralose. Additionally, health regulatory and food safety authorities have found other studies conducted by the Ramazzini Institute to be unreliable. The group routinely conducts studies using an unconventional design and has been criticized for not following internationally-recognized safety assessment standards.

The truth is that the collective scientific evidence strongly supports that sucralose is safe and does not cause cancer. Sucralose has been extensively researched, with more than 110 studies conducted over a 20-year period. These studies include rigorous testing to specifically identify any potential for causing cancer. Worldwide regulatory authorities, including the U.S. Food and Drug Administration, the European Food Safety Authority, Health Canada and the World Health Organization, have reviewed these studies and confirm that results show no link between sucralose and cancer. The U.S. National Cancer Institute also supports this conclusion.

Our society faces significant health risks with obesity and being overweight, including complications like diabetes and cardiovascular disease. Research indicates that one contributor to becoming overweight can be excess intake of added sugars. As a consequence, the current U.S. Dietary Guidelines, the World Health Organization and the American Heart Association have all recommended a reduction in average sugar consumption. Low-calorie sweeteners, like Splenda, are effective tools for consumers to reduce their added sugar intake, helping them to lead healthier lives.

This latest study by the Ramazzini Institute is just one more example of the type of report that perpetuates misperceptions about low-calorie sweeteners. Extensive research strongly supports that sucralose is safe for everyone and does not cause cancer. That is why Splenda Sweeteners are recommended by health care professionals every day and are safely used by millions of people with a variety of health conditions, such as diabetes, obesity and being overweight.

For more information about low-calorie sweeteners, please visit

ABOUT Splenda Sweetener Products

Sucralose, the sweetening ingredient in Splenda Sweetener Products, has been used safely by millions of people around the world for more than 20 years, supported by research data from more than 100 studies. Both the American Diabetes Association (ADA) and the Academy of Nutrition and Dietetics (AND) support the use of low calorie sweeteners such as sucralose as a useful tool in weight management and diabetes. For more information about sucralose or the Splenda Brand, visit You can also follow the Splenda Brand on TumblrFacebookInstagram and Pinterest.

About Heartland Food Products Group

Based outside of Indianapolis, Heartland Food Products Group is a global leader in the production of low-calorie sweetener products, creamers, beverage concentrates, coffee, and nutritional drinks. Visit Heartland at