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“All [five nonnutritive sweeteners] underwent rigorous scrutiny and were shown to be safe when consumed by the public, including people with diabetes.” – American Diabetes Association

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American Diabetes Association

“The FDA has approved five nonnutritive sweeteners for use in the U.S. These are acesulfame potassium, aspartame, neotame, saccharin, and sucralose. Before being allowed on the market, all underwent rigorous scrutiny and were shown to be safe when consumed by the public, including people with diabetes and women during pregnancy. Clinical studies involving subjects without diabetes provide no indication that nonnutritive sweeteners in foods will cause weight loss or weight gain.”

– American Diabetes Association

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American Heart Association

“The American Heart Association recommends cutting back on added sugars. Using low- and no-calorie sweeteners is one option that may help in an overall healthy diet. Foods and beverages containing low- and no-calorie sweeteners can be included in a healthy eating plan, as long as the calories they save are not added back as a reward or compensation. The FDA has determined that certain low- and no-calorie sweeteners, such as sucralose, are safe.”

– American Heart Association

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National Cancer Institute

“Sucralose was approved by the Food and Drug Administration (FDA) as a tabletop sweetener in 1998, followed by approval as a general purpose sweetener in 1999. Before approving sucralose, the FDA viewed more than 100 safety studies that were conducted, including studies to assess cancer risk. The results of these studies showed no evidence that these sweeteners cause cancer or pose any other threat to human health.”

– National Cancer Institute

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Academy of Nutrition and Dietetics

“It is the position of the Academy of Nutrition and Dietetics that consumers can safely enjoy a range of nutritive and nonnutritive sweeteners when consumed within an eating plan that is guided by current federal nutrition recommendations, such as the Dietary Guidelines for Americans and the Dietary Reference Intakes, as well as individual health goals and personal preference.”

– Academy of Nutrition and Dietetics

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American Cancer Society

"Do non-nutritive sweeteners or sugar substitutes cause cancer? There is no proof that these sweeteners, at the levels consumed in human diets, cause cancer."

– American Cancer Society

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American Academy of Family Physicians

“More than 110 studies have examined the safety of sucralose. It has been approved by the FDA as a food additive since 1998. According to the National Cancer Institute, there is no evidence that sucralose and other sugar substitutes approved for use in the United States cause cancer or other serious health problems.”

– American Academy of Family Physicians

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American Academy of Pediatrics

“Additional improvements in nutrient density of sweet-tasting products could be obtained if nonnutritive sweeteners [also known as low calorie sweeteners] are used as a tool to replace added sugars and help lower caloric intake.”

– American Academy of Pediatrics

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U.S. Food and Drug Administration

"In determining the safety of sucralose, FDA reviewed data from more than 110 studies in animals and humans. Many of these studies were designed to identify possible toxic effects including carcinogenic, reproductive and neurological effects. No such effects were found and FDA's approval is based on finding that sucralose is safe for human consumption."

– U.S. Food and Drug Administration

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European Commission

"There is adequate evidence [for sucralose] that there are no concerns about mutagenicity, carcinogenicity, development or reproductive toxicity."

– European Commission